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Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL. Having a therapy that has been shown to address multiple symptoms of Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families. Findings showed that treatment with trofinetide were diarrhea and can estrace cream cause hot flashes vomiting.

I am thrilled to now be able to offer Daybue to more people living with Rett syndrome, outside of a clinical trial. Rett syndrome in adult and pediatric patients 2 years of age and older. Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL.

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What side effects may I notice from Estrace?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• breast tissue changes or discharge
• changes in vision
• chest pain
• confusion, trouble speaking or understanding
• dark urine
• general ill feeling or flu-like symptoms
• light-colored stools
• nausea, vomiting
• pain, swelling, warmth in the leg
• right upper belly pain
• severe headaches
• shortness of breath
• sudden numbness or weakness of the face, arm or leg
• trouble walking, dizziness, loss of balance or coordination
• unusual vaginal bleeding
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Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• hair loss
• increased hunger or thirst
• increased urination
• symptoms of vaginal like itching, irritation or unusual discharge
• unusually weak or tired

This list may not describe all possible side effects.

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